Zeno of Citium, a Phoenician merchant whose ship had been wrecked off the Piraeus, took up philosophy in Athens around 312 BCE. He studied with the Cynic Crates, then with members of the Academy and the Megarian school. Around 300 BCE he began teaching in the Stoa Poikile — the Painted Porch on the agora's north side. His successors Cleanthes and Chrysippus systematised the doctrine; the school flourished for five centuries.
Three classical periods are usually distinguished. The Old Stoa (Zeno, Cleanthes, Chrysippus, c. 300–150 BCE) — its writings now mostly lost. The Middle Stoa (Panaetius, Posidonius, c. 150–50 BCE) — the school's transmission to Rome. The Roman Stoa (Seneca, Musonius Rufus, Epictetus, Marcus Aurelius, c. 50 BCE–180 CE) — the period from which most surviving texts come.